Has anyone bothered to tune the Knight, Mercenary, Noble, Prankster, or Rebel chemistries for their lineups?
As best as I can tell, these chemistries generally accomplish the following when maxed out:
Knight: Blocking
Mercenary: Defensive
Noble: Blocking
Prankster: Ball carrier
Rebel: Defensive and Blocking
Knight feels the most incoherent of these boosts. Noble and Prankster feel like they could be good enough boosted to 6/9.
A lot of the players that have these chemistries are in positions where they don't directly benefit from them, meaning you focus primarily on tuning the wildcard players: The Most Feared Upgradable Champions, Most Feared Event Champions, and Shapeshifters.
If you have an Epic Team Chemistry item, you can get up to two different Most Feared auxiliary chemistries to 9/9. I can achieve 6/9 on one chemistry and max out on another between Rebel and Prankster, the two chemistries naturally provided by the Most Feared Raiders theme team. I've opted for 6/9 Prankster and 9/9 Rebel.
(Special Note: We've received one 2x Most Feared auxiliary chemistry for each chemistry except for Noble. With two LTD's per week, perhaps the next release provides a second 2x Most Feared auxiliary chemistry player, making a pair of 9/9 chemistries possible, although these of course will not stack.)