What is Chemistry in Madden Ultimate Team 25?
There are two types of chemistry in MUT: standard NFL team chemistry and special chemistry tied to MUT programs. Each chemistry has several ratings boosts that are unlocked by achieving a set amount of instances of that chemistry in your lineup. Typically, these boosts target every player in your lineup with the associated chemistry equipped.
Nearly every player item in MUT can equip one or more chemistry. To modify a player item's chemistry, use the Upgrades tab after selecting a single player item. Theme Teams can be constructed based on a single chemistry or by combining multiple chemistry types in the same lineup.