I see people running this all the time now
Basically you can have any 2 WRs (blocking stats dont matter) and they dominantly block your defending DBS, so the TE gets a wide open catch outside
I've tried Man press, 0 drop zone flats.
All my DBs get blocked...the only way I can counter this is to manually lurk with my DE on that side
https://www.madden-school.com/playbooks/bears/offense/pistol/u-off-trips/rpo-alert-flat/